Can phage effectively treat multidrug-resistant plague?

Figures & data

Table 1. Bacteriophages lytic for Y. pestis – potential components of therapeutic cocktails

Bacteriophage	Group	Cell wall receptor*	Reference(s) and/or sequence No.
Pokrovskaya (YepE2, YpP-G)	T7	HepII/HepIII	9,10; NC_011038; JQ965702
φA1122	T7	KdoI/KdoII	9–14; NC_004777
Y (YpP-Y)	T7	HepI/Glc	9,10; JQ965700
R (YpP-R)	T7	Beyond LPS core	9,10; JQ965701
d’Herelle-m (YpsP-G)	T7	ND^†	10; JQ965703
Yep-phi	T7	ND	15; HQ333270
Berlin	T7	ND	NC_008694
PST	T4	HepII/HepIII	9,10
φJA1*	T4	KdoI/KdoII	9,10
PY100	T1	ND	16; AM076770
L-413C	P2	GlcNAc	9–11,13,17; NC_004745

* Sugar residues of Y. pestis lipopolysaccharide (LPS) critical for phage receptor structure are presented. ^†ND, not determined.