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Commentary

The tumor suppressor gene ARHI(DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms

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Pages 232-236 | Received 15 Nov 2012, Accepted 17 Jan 2013, Published online: 28 Jan 2013

Figures & data

Figure 1. ARHI expression inhibits integrin β1 expression. The re-expression of ARHI decreased the expression of integrin β1 indicated by arrows. SKOv3-ARHI cells were treated with doxycycline (DOX) for the indicated time periods to induce ARHI expression. The expression of integrin β1 was examined by western blotting.

Figure 1. ARHI expression inhibits integrin β1 expression. The re-expression of ARHI decreased the expression of integrin β1 indicated by arrows. SKOv3-ARHI cells were treated with doxycycline (DOX) for the indicated time periods to induce ARHI expression. The expression of integrin β1 was examined by western blotting.

Figure 2. ARHI can inhibit cell migration through several mechanisms. A proposed model of ARHI action in a scheme.

Figure 2. ARHI can inhibit cell migration through several mechanisms. A proposed model of ARHI action in a scheme.

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