Figures & data
Figure 1 Highly sialylated Neural Cell Adhesion Molecule (PSA-NCAM) in adult brain cell populations involved in different types of synaptic plasticity. Top: diagrammatic representation of sagittal (A) and coronal (B) views of the rat brain showing areas containing cells enriched in PSA-NCAM. In grey, neurogenic sites. H, hippocampus; OB, olfactory bulb; OM, olfactory mucosa; PC, piriform cortex; SON, supraoptic nucleus; SVZ, subventricular zone. Bottom: Immunoreactions for polysialic acid (PSA) reveal highly immunopositive neurons (C, D and F) in restricted areas known to undergo plasticity, like the olfactory bulb (C), hippocampus (D) and the piriform cortex (F). In neuroendocrine centers like the SON (E), a strong reaction fills the neuropile and is due to immunoreaction on neuronal and glial (astrocytic) processes. Note that newly generated (top, green nuclei) and non-newly generated cells (top, unstained nuclei) display a typical punctate reaction on their cell membrane (see also C and D). DCX, doublecortin.
