Adult primary pulmonary primitive neuroectodermal tumor

Figures & data

Figure 1. Chest radiogram of a 31-y-old man with primary pulmonary primitive tumor (PNET) in the left lung (lingula).

Figure 2. Computer tomographic scan of a 31-y-man with primary pulmonary primitive tumor (PNET) in the left lung.

Figure 3. Well demarcated primary pulmonary primitive tumor (PNET) with extensive tumor necrosis inside.

Figure 4. HH&E stained section of a small round cell lung tumor-primary pulmonary tumor (PNET).

Figure 5. Schematic diagram of EWS-FLI1 gene fusion resulting from t(22;11) translocation. The TET family associated RRM domain, the ETS DNA-binding domain (ETS-DBD) and the N-terminal transactivation domain (ATA) are shown. The fusion gene can vary depending on whether exons 5–9 or 6–9 of FLI1 are included. Adapted with permission from ref. 10.

Table 1. A literature summary of case reports of Primary Primitive Neuroectodermal Tumor (PNET) of the lung/chest wall

Authors - journal - year	Title
1. Burge HJ, Novotny DB, Schiebler ML, Delany DJ, McCartney WH, Chest. Vol 97, 1252–1254, 1990	MRI of Askin’s tumor. A case report at 1.5 T.
2. Cabezali R, Lozano R, Bustamante E, Castiella T, Güemes A, Ramírez J, Moncada E et al., Journal of Thoracic and Cardiovascular Surgery. Vol 107, 960–962, 1994	Askin’s tumor of the chest wall: a case report in an adult.
3. Imamura F, Funakoshi T, Nakamura S, Mano M, Kodama K, Horai T, Lung cancer, Vol 27, 55–60, 2000	Primary primitive neuroectodermal tumor of the lung: report of two cases.
4. Baumgartner FJ, Omari BO, French SW, Ann Thorac Surg, Vol 72, 285–287, 2001	Primitive Neuroectodermal Tumor of the Pulmonary Hilum in an Adult.
5. Kahn AG, Avagnina A, Nazar J, Elsner B, Arch Patho Med, Vol 125, 397–399, 2001	Primitive neuroectodermal tumor of the lung.
6. Paik SH, Park JS, Koh ES, Kim HK, Shin HK, Hong HS et al., European Radiology, Vol 16,2138–2131, 2006	Primary pulmonary primitive neuroectodermal tumor: CT and skeletal scintigraphic image features with pathologic correlation.
7. Lee YY, Kim DH, Lee JH, Choi JS, In KH, Oh YW et al. J Korean Med Sci, Vol 22, 159–163, 2007	Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-y-old Man.
8. Verma S, Prakash P, Yadav P, Srivastava D, Sharma SC, JIACM, Vol 9,237–239, 2008	Primitive Neuroectodermal Tumour of the Chest Wall in an Adult.
9. Antelo JS, García CR, Martínez CM, Hernando HV, Arch Bronconeumol, Vol 46, 44–46, 2010	Pulmonary Ewing Sarcoma/Primitive Neuroectodermal Tumor: A Case Report and a Review of the Literature.
10. Gedik GK, Sari O, Altinok T, Tavli T, Kaya B, Kara PO, Case Report in Medicine, Article ID 517329, 2009	Askin's Tumor in an Adult: Case Report and Findings on 18F-FDG PET/CT.
11. Gaude GS, Malur PR, Kangale R, Anurshetru S, Lung India, Vol 26, 89–91, 2009	Primitive neuro-ectodermal tumor of the lung in an adult.
12. Guade GS, Patil P, Mlur P, Annurshetru S, Journal Of Thoracic Disease, Vol 3, 2011	Premitive neuro-ectodermal tumor of the lung.
13. Weissferdt A, Moran CA, Lung, July 17, 2012	Primary Pulmonary Primitive Neuroectodermal Tumor (PNET): A Clinicopathological and Immunohistochemical Study of Six Cases.

Riggi N, Stamenkovic I. The Biology of Ewing sarcoma. Cancer Lett 2007; 254:1 - 10; http://dx.doi.org/10.1016/j.canlet.2006.12.009; PMID: 17250957

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