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Cell Cycle News & Views

Function following form

Functional differentiation of mammary epithelial cells requires laminin-induced polarization of PI3-kinase

Pages 15-22 | Published online: 01 Jan 2011

Figures & data

Figure 1 Virgin daughters are more sensitive to acetic acid or heat stress than young mothers in (A) wild type and (B) Δsir2 strain. Crosses represent stress-induced death, where the size of the cross correlates with the death rate. Each scar depicts a division event. The red circles represent the total amount of damage, which is in wild type retained by the mother cell and in the Δsir2 strain distributed between the mother and the daughter. Thus, virgin Δsir2 daughters are more sensitive to stress than virgin wild-type daughters. Old Δsir2 mothers, on the other hand, are less sensitive to stress than old wild-type mothers, because Δsir2 mothers accumulate less damage.

Figure 1 Virgin daughters are more sensitive to acetic acid or heat stress than young mothers in (A) wild type and (B) Δsir2 strain. Crosses represent stress-induced death, where the size of the cross correlates with the death rate. Each scar depicts a division event. The red circles represent the total amount of damage, which is in wild type retained by the mother cell and in the Δsir2 strain distributed between the mother and the daughter. Thus, virgin Δsir2 daughters are more sensitive to stress than virgin wild-type daughters. Old Δsir2 mothers, on the other hand, are less sensitive to stress than old wild-type mothers, because Δsir2 mothers accumulate less damage.

Figure 1 Schematic showing the differing levels of H3Ser10 phosphorylation during the various stages of mitosis in somatic cells (blue) and in the first two embryonic divisions (red). (P, prophase; M, metaphase; A, anaphase; T, telophase).

Figure 1 Schematic showing the differing levels of H3Ser10 phosphorylation during the various stages of mitosis in somatic cells (blue) and in the first two embryonic divisions (red). (P, prophase; M, metaphase; A, anaphase; T, telophase).