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Editorials: Cell Cycle Features

Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans

, , &
Pages 4294-4295 | Published online: 24 Oct 2012

Figures & data

Figure 1. Transcriptional regulators Flo8, Mss11 and the newly identified Mfg1 form a complex and control expression of key morphogenetic determinants in both C. albicans and S. cerevisiae, thereby regulating the transitions from yeast to filamentous growth. This model depicts these three transcription factors regulating FLO11 in S. cerevisiae, but C. albicans lacks a FLO11 ortholog, suggesting that the targets of this complex have been rewired between the two species.

Figure 1. Transcriptional regulators Flo8, Mss11 and the newly identified Mfg1 form a complex and control expression of key morphogenetic determinants in both C. albicans and S. cerevisiae, thereby regulating the transitions from yeast to filamentous growth. This model depicts these three transcription factors regulating FLO11 in S. cerevisiae, but C. albicans lacks a FLO11 ortholog, suggesting that the targets of this complex have been rewired between the two species.