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Editorials: Cell Cycle Features

Counteracting stem cell expansion during wound repair

Distinct roles of non-canonical Wnt and TGF-β

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Pages 387-388 | Published online: 16 Jan 2013

Figures & data

Figure 1. Schematic of crypt regeneration during the colonic wound healing. After injury, an adjacent crypt expands into the wound bed and forms a wound channel. In parallel, Wnt5a-positive mesenchymal cells focally suppress proliferation of adjacent epithelial cells in the wound channel and induce its subdivision into crypts.

Figure 1. Schematic of crypt regeneration during the colonic wound healing. After injury, an adjacent crypt expands into the wound bed and forms a wound channel. In parallel, Wnt5a-positive mesenchymal cells focally suppress proliferation of adjacent epithelial cells in the wound channel and induce its subdivision into crypts.