Figures & data
Figure 1. Schematic overview over steady-state granulopoiesis. PAMPs (pathogen-associated molecular patterns) may originate from the dense intestinal microflora and bind to PRRs (pattern recognition receptors) expressed by both hematopoietic and non-hematopoietic TLR4+ sensing cells forming the neutrostat. Downstream signaling pathways culminate in G-CSF dependent granulopoiesis. Mϕ, macrophage.
