Figures & data
Figure 1 ABA production in T. gondii. (A) Cross-section through an intracellular T. gondii showing organellar structures. Insert illustrates four surrounding membranes from enlarged apicoplast. N, nucleus; A, apicoplast; AC, apical complex consisting of conoid and secretory organelles; PV, parasitophorous vacuole. (B) Model of ABA production by the parasite with in the PV. Accumulation of ABA (pink) leads to increases in intracellular calcium (blue) activating egress and triggering secretion of micronemes (MICs shown in green). Fluridone blocks ABA production, preventing egress and favoring differentiation of tissue cysts.
![Figure 1 ABA production in T. gondii. (A) Cross-section through an intracellular T. gondii showing organellar structures. Insert illustrates four surrounding membranes from enlarged apicoplast. N, nucleus; A, apicoplast; AC, apical complex consisting of conoid and secretory organelles; PV, parasitophorous vacuole. (B) Model of ABA production by the parasite with in the PV. Accumulation of ABA (pink) leads to increases in intracellular calcium (blue) activating egress and triggering secretion of micronemes (MICs shown in green). Fluridone blocks ABA production, preventing egress and favoring differentiation of tissue cysts.](/cms/asset/8ca826e4-a2fb-4535-9cee-5ef308b4fe51/kcib_a_10906106_f0001.gif)
Figure 2 Biosynthetic pathways for ABA production in higher plants and fungi. This is an abbreviated scheme showing only the major steps in the pathways. For further details consult.Citation24,Citation25,Citation28 DOXP, deoxy-D-xylulose-5-phosphate; FPS, farnesyl diposphate synthase; GGPS, geranylgeranyl diphosphate synthase; PSY, phytoene synthase; PDS, phytoene desaturase; ZEP, zeaxanthin epoxidase; NSY, neoxanthin synthase; NCED, 9-cis-epoxycarotenoid dioxygenase; ABA, abscisic acid.
![Figure 2 Biosynthetic pathways for ABA production in higher plants and fungi. This is an abbreviated scheme showing only the major steps in the pathways. For further details consult.Citation24,Citation25,Citation28 DOXP, deoxy-D-xylulose-5-phosphate; FPS, farnesyl diposphate synthase; GGPS, geranylgeranyl diphosphate synthase; PSY, phytoene synthase; PDS, phytoene desaturase; ZEP, zeaxanthin epoxidase; NSY, neoxanthin synthase; NCED, 9-cis-epoxycarotenoid dioxygenase; ABA, abscisic acid.](/cms/asset/90b4422d-771e-4146-99ae-0e2f9e8b4139/kcib_a_10906106_f0002.gif)