How and why does Dia1 mRNA localize?

Figures & data

Figure 1 Working model of Dia1 mRNA localization on the perinuclear ER.

Figure 2 Predicted potential translation pausing motif (CTR) in chicken and human Dia1 protein sequences. The CTR sequences are from reference 10. The CTR in both chicken and human Dia1 are overlapped with a portion of the GBD.

Yanagitani K, Kimata Y, Kadokura H, Kohno K. Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA. Science 2011; 331:586 - 589

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