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Mini Review

Mouse models to investigate the function of spermine

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Pages 271-274 | Received 16 Feb 2009, Accepted 17 Feb 2009, Published online: 15 Jun 2009

Figures & data

Figure 1 Polyamine structure and biosynthesis/interconversion. The abbreviations used are dcAdoMet, decarboxylated S-adenosylmethionine; MTA, 5′-methylthioadenosine; ODC, L-ornithine decarboxylase; APO, acetylpolyamine oxidase; SMO spermine oxidase; SSAT, spermidine/spermine-N1-acetyltransferase; ND, not detected.

Figure 1 Polyamine structure and biosynthesis/interconversion. The abbreviations used are dcAdoMet, decarboxylated S-adenosylmethionine; MTA, 5′-methylthioadenosine; ODC, L-ornithine decarboxylase; APO, acetylpolyamine oxidase; SMO spermine oxidase; SSAT, spermidine/spermine-N1-acetyltransferase; ND, not detected.

Figure 2 Gy, control and Gy/CAG-SMS mice. The upper panel shows four week old control and Gy mouse (B6C3H background). The lower panel shows Gy and Gy/CAG-SMS mice originating from crosses of Gy (B6C3H) and CAG-SMS (B6D2).

Figure 2 Gy, control and Gy/CAG-SMS mice. The upper panel shows four week old control and Gy mouse (B6C3H background). The lower panel shows Gy and Gy/CAG-SMS mice originating from crosses of Gy (B6C3H) and CAG-SMS (B6D2).