Does a physiological role for KCNE subunits exist in the immune system?

Figures & data

Figure 1 Human KCNE expression in healthy and cancer tissues. Affymetrix GeneChips HG-U95A-E (GeneNote, http://bioinfo2.weizmann.ac.il/cgi-bin/genenote/home_page.pl) and HG-U133A (GNF, (http://biogps.gnf.org) normalized as described in GeneCard (http://www.genecards.org). Black columns: healthy tissue (GeneNote); Grey columns: healthy tissues (GNF); White columns: cancer samples (GNF).

Figure 2 KCNE expression in human leukocytic cell lines. Array data from GNF BioGPS (http://biogps.gnf.org) normalized according to Su et al.31 Legend: CD34, bone marrow CD34⁺ progenitors; CD105, endothelial; X212, B lymphoblasts; CD19, B cells; BDCA4, dendritic cells; CD8, CD8⁺ Tcells; CD4, CD4⁺ T-cells; CD56, NK cells; CD33, myeloid; CD14, monocytes.

Figure 3 KCNE expression in different human leukemia and lymphoma cell lines. Array data from GNF BioGPS (http://biogps.gnf.org) normalized according to Su et al.31 Legend: MOLT4, Lymphoblastic Leukemia; K.582, Chronic Myelogenous Leukemia; Daudi, Burkitt’s Lymphoma; HL60, Promyelocytic Leukemia; Raji, Burkitt’s Lymphoma.

Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 2004; 101:6062 - 6067

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