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Article Addendum

PfeIF4E and PfeIF4A colocalize and their double-stranded RNA inhibits Plasmodium falciparum proliferation

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Pages 611-613 | Received 20 Aug 2010, Accepted 23 Aug 2010, Published online: 01 Nov 2010

Figures & data

Figure 1 (A–D) Immunofluorescence assay of PfeIF4E (B) and PfeIF4A (C) respectively in fixed parasite cultures showing co-localization (D). (E) Effect of dsRNA on in vitro growth of the parasite. The relative growth of unsynchronized cultures at various time-points after treatment with dsRNA was measured and plotted. The results are represented as percent inhibition of the growth compared to control cultures. The bars indicate standard deviation. The curves are as follows: (a) cultures treated with PfeIF4A and PfeIF4E dsRNA; (b) cultures treated with PfeIF4A dsRNA; (c) cultures treated with PfeIF4E dsRNA; and (d) cultures treated with control GFP dsRNA.

Figure 1 (A–D) Immunofluorescence assay of PfeIF4E (B) and PfeIF4A (C) respectively in fixed parasite cultures showing co-localization (D). (E) Effect of dsRNA on in vitro growth of the parasite. The relative growth of unsynchronized cultures at various time-points after treatment with dsRNA was measured and plotted. The results are represented as percent inhibition of the growth compared to control cultures. The bars indicate standard deviation. The curves are as follows: (a) cultures treated with PfeIF4A and PfeIF4E dsRNA; (b) cultures treated with PfeIF4A dsRNA; (c) cultures treated with PfeIF4E dsRNA; and (d) cultures treated with control GFP dsRNA.