A retrospective study of thyroid structural abnormalities in alopecia patients

Figures & data

Figure 1 Results of manual thyroid exam, thyroid function tests and subsequent ultrasound evaluation flowchart. nl, normal; hx, history; abnl, abnormal; U/S, ultrasound; w/u, work-up; pts, patients; dz, disease; dx, diagnosis; TFT, thyroid function test (serum).

Table 1 Demographic features of the study population who received manual thyroid exam

Characteristic	Valuea
Mean age (yrs) +/− SD	44.1 +/− 16.7
Female	325/367 (88.6)
F:M ratio	7.7:1
White	267/367 (72.8)
Non scarring Alopecia	318/367 (86.6)
Scarring Alopecia	49/367 (13.4)

a Unless otherwise indicated, data are reported as number of patients in the recorded category/total number of patients in the study (%).

Table 2 Type of hair loss in patients with abnormal ultrasound evaluations

Type of Hair Loss	Number of Patientsa
Non Scarring Alopecia
Telogen Effluvium	12/41 (29.3)
Androgenic Alopecia	10/41 (27.8)
Alopecia Areata	10/41 (24.4)
Traction Alopecia	4/41 (9.8)
Scarring Alopecia
Central Centrifugal Cicatricial Alopecia	3/41 (7.3)
Lichen Planopilaris	1/41 (2.4)
Scarring Alopecia NOS	1/41 (2.4)

a Data are reported as number of patients in the recorded category/total number of patients with abnormal ultrasound evaluations (%).

Table 3 Results of abnormal ultrasound with associated alopecia

aSonographic Abnormality: Number	Type of Alopecia: Number of Patients
*Nodule with concerning features: 4	Alopecia Areata: 2
	TE: 2
>1cm nodule: 5	Alopecia Areata: 1
	TE: 1
	Androgenic Alopecia: 1
	Traction: 2
+Adenopathy: 8	Alopecia Areata: 3
	Androgenic Alopecia: 4
	Traction: 1
Subcentimeter nodule: 18	Alopecia Areata: 4
	TE: 6
	Androgenic Alopecia: 5
	Traction: 2
	CCCA : 1
Cyst: 9	Alopecia Areata: 2
	TE: 1
	Androgenic Alopecia: 3
	CCCA : 2
	Traction: 1
Thyromegaly: 7	Alopecia Areata: 2
	TE: 1
	Androgenic Alopecia: 1
	Traction: 1
	LPP: 1
	Scarring Alopecia NOS: 1

a 51 total abnormalities were discovered on ultrasound (1 patient had 3 abnormalities and 8 patients had 2 abnormalities).