Figures & data
Figure 1 Sex differences in epigenetic mechanisms underlie risk and resilience for mental health disorders. Gene and environmental interactions remodel chromatin structure by recruiting co-regulatory proteins and other transcription factors resulting in either increased or decreased gene transcription rates. These interactions can lead to methylation or demethylation of DNA, as well as acetylation or deacetylation of histones. Lasting chromosomal alterations that impact gene and brain function can lead to gender specific altered risk or resilience to neurodevelopmental disorders later in life.
