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Research Paper

The relationship between tumor MSLN methylation and serum mesothelin (SMRP) in mesothelioma

, , , , , , , , , & show all
Pages 1029-1034 | Received 11 Mar 2011, Accepted 10 Jun 2011, Published online: 01 Aug 2011

Figures & data

Figure 1 Distribution of serum SMRP among cases (red) and non-diseased controls (blue).

Figure 1 Distribution of serum SMRP among cases (red) and non-diseased controls (blue).

Figure 2 CpG methylation at the MSLN gene is lower in tumor compared to normal pleura and lower in tumors from SMRP serum positive compared to serum negative cases.

Figure 2 CpG methylation at the MSLN gene is lower in tumor compared to normal pleura and lower in tumors from SMRP serum positive compared to serum negative cases.

Figure 3 Methylation class, derived from a recursively partitioned mixed model of methylation at 1500 CpG sites, is associated with serum SMRP levels.

Figure 3 Methylation class, derived from a recursively partitioned mixed model of methylation at 1500 CpG sites, is associated with serum SMRP levels.

Table 1 Demographic and clinical traits of studied mesothelioma cases

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