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Article Addendum

Antimicrobials

Strategies for targeting obesity and metabolic health?

, , , , , , , & show all
Pages 48-53 | Published online: 27 Sep 2012

Figures & data

Figure 1. Schematic overview of the effect of bacteriocin-producing probiotic Lactobacillus salivarius UCC118 and oral vancomycin on the composition of the gut microbiota at family level in diet-induced obese mice.

Figure 1. Schematic overview of the effect of bacteriocin-producing probiotic Lactobacillus salivarius UCC118 and oral vancomycin on the composition of the gut microbiota at family level in diet-induced obese mice.

Figure 2. Acetate and propionate production (µmol/g) over the 8 week intervention period in (1) lean, DIO and vancomycin-treated DIO mice and (2) DIO mice treated with the bacteriocin-producing probiotic strain L. salivarius UCC118 Bac+ (1 × 109 cfu/day) compared with DIO mice treated with a non-bacteriocin-producing derivative L. salivarius UCC118Bac- (1 × 109 cfu/day). Data represented as mean ± SEM, n = 9–10. *p < 0.05

Figure 2. Acetate and propionate production (µmol/g) over the 8 week intervention period in (1) lean, DIO and vancomycin-treated DIO mice and (2) DIO mice treated with the bacteriocin-producing probiotic strain L. salivarius UCC118 Bac+ (1 × 109 cfu/day) compared with DIO mice treated with a non-bacteriocin-producing derivative L. salivarius UCC118Bac- (1 × 109 cfu/day). Data represented as mean ± SEM, n = 9–10. *p < 0.05

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