Group A rotavirus genotypes circulating prior to implementation of a National Immunization Program in Estonia

Figures & data

Figure 1. Number of registered group A rotaviral gastroenteritis cases per 100 000 persons per year from 1999 to 2010 according to Estonian Health Board (www.terviseamet.ee/en.html). Note that 75–91% of cases have been hospitalized.

Figure 2. Age distribution of the hospitalised group A rotaviral gastroenteritis patients in Estonia in 2007 to 2008. Note that maximum value of Y axis is 45%.

Table 1. Clinical characteristics of children with group A rotaviral gastroenteritis

Characteristics Severity according to Clark scoring system mild (< 9 points) moderate (9–16 points) severe (> 16 points) ND	Number of patients (%) 97 (14.5) 516 (76.9) 51 (7.6) 7 (1.0)
Degree of dehydration (% of weight) mild < 3% moderate 3–9% severe > 9% ND	412 (61.4) 182 (27.1) 10 (1.5) 67 (10.0)
Treatment of rehydration oral rehydration only combination of oral and i/v rehydration i/v rehydration only	25 (3.7) 646 (96.3) 0

ND, not determined

Table 2. G- and P-genotype combinations by year

Genotype	Number (%) of strains
	2007	2008	Total
Total	72 (58.1)	52 (41.9)	124
Common human rotavirus strains	44 (61.1)	27 (51.9)	71 (57.3)
G1P[8]	2 (2.8)	3 (5.8)	5 (4.0)
G2P[4]	38 (52.8)	5 (9.6)	43 (34.7)
G3P[8]	2 (2.8)	0	2 (1.6)
G4P[8]	2 (2.8)	14 (26.9)	16 (12.9)
G9P[8]	0	5 (9.6)	5 (4.0)
Uncommon human reassortants	4 (5.6)	0	4 (3.2)
G1P[4]	1 (1.4)	0	1 (0.8)
G2P[8]	1 (1.4)	0	1 (0.8)
G4P[4]	2 (2.8)	0	2 (1.6)
Others	1 (1.4)	1 (1.9)	2 (1.6)
G1P[11]	0	1 (1.9)	1 (0.8)
G2P[6]	1 (1.4)	0	1 (0.8)
Mixed infections	3 (4.2)	2 (3.8)	5 (4.0)
Dual G-type	2 (2.8)	0	2 (1.6)
Dual P-type	1 (1.4)	2 (3.8)	3 (2.4)
Untypeable strains	20 (27.8)	22 (42.3)	42 (33.9)
G-untypeable	4 (5.6)	0	4 (3.2)
P-untypeable	16 (22.2)	21 (40.4)	37 (29.8)
G- and P-untypeable	0	1 (1.9)	1 (0.8)