Acute gastroenteritis hospitalizations among children aged < 5 years before and after introduction of rotavirus vaccines

Figures & data

Table 1. Number of hospitalizations (%) related to rotavirus gastroenteritis and gastroenteritis of all causes in children aged < 5 y

	Rotavirus infection							All cause AGE
Age group	2003–2004	2004–2005	2005–2006	2006–2007	2007–2008	2008–2009	2009–2010	2003–2004	2004–2005	2005–2006	2006–2007	2007–2008	2008–2009	2009–2010
< 12 m	117 (47.2)	135 (43.7)	214 (48.9)	131 (47.8)	127 (47.2)	96 (35.6)	64 (35.4)	212 (40.2)	248 (41.7)	303 (42.7)	216 (45.1)	213 (45.2)	167 (37.4)	113 (33.7)
12 -23 m	72 (29.0)	103 (33.3)	130 (29.7)	83 (29.7)	87 (32.3)	99 (36.7)	60 (33.1)	139 (26.3)	178 (29.9)	216 (30.5)	132 (27.6)	136 (28.9)	152 (34.0)	120 (35.8)
24–35 m	33 (13.3)	38 (12.3)	63 (14.4)	37 (13.5)	34 (12.6)	41 (15.2)	29 (16.0)	81 (15.3)	79 (13.3)	117 (16.5)	70 (14.6)	65 (13.8)	66 (14.8)	53 (15.8)
36–59 m	26 (10.5)	33 (10.7)	31 (7.1)	23 (8.4)	21 (7.8)	34 (12.6)	28 (15.5)	96 (18.2)	90 (15.1)	73 (10.3)	61 (12.7)	57 (12.1)	62 (13.9)	49 (14.6)
Total	248 (100)	309 (100)	438 (100)	274 (100)	269 (100)	270 (100)	181 (100)	528 (100)	595 (100)	709 (100)	479 (100)	471 (100)	447 (100)	335 (100)

Table 2. Annual rates of hospitalizations due to acute infectious gastroenteritis and rotavirus gastroenteritis in children aged < 5 y

Study period	Acute infectious gastroenteritis
	Rotavirus infection		All etiologies
	No. hospitalizations	Rate x 100,000	No. hospitalizations	Rate x 100,000
July 2003 to June 2004	248	270.0	528	574.9
July 2005 to June 2005	309	324.1	595	624.1
July 2005 to June 2006	438	444.7	709	719.8
July 2006 to June 2007	274	271.2	479	474.2
July 2007 to June 2008	269	259.9	471	455.1
July 2008 to June 2009	270	253.8	447	420.2
July 2009 to June 2010	181	165.3	335	306.0

Table 3. Changes in hospitalization rates due to acute infectious gastroenteritis and rotavirus gastroenteritis in children aged < 5 y

Study period	Acute infectious gastroenteritis children aged < 5 y		Acute infectious gastroenteritis children aged < 1 y
	Rotavirus infection	All etiologies	Rotavirus infection	All etiologies
Pre-vaccination
Median hospitalization rate x100.000 for the period July 2003 -June 2007	297.7	599.5	696.2	1,269.7
Post-vaccination
Annual hospitalization rate x100.000 July 2008-June 2009 (% decrease)	253.8 (14.8)	420.2 (29.9)	473.3 (32.0)	823.4 (35.2)
Annual hospitalization rate x100.000 July 2009-June 2010 (% decrease)	165.3 (44.5)	306.0 (49.0)	297.1 (57.3)	524.5 (58.7)

Note: * Transition period between July 2007 and June 2008 was excluded for this analysis

Figure 1. Annual hospitalization rates for rotavirus-related AGE and acute gastroenteritis (AGE) of all causes in Galicia from June 2003 to July 2010 by group of age. (A) Hospitalization rates RV-AGE. (B) Hospitalization rates all cause-AGE.

Table 4. Monthly number of hospitalizations related to rotavirus gastroenteritis and acute gastroenteritis (AGE) of all causes in children aged < 5 y

Months	Monthly number of hospitalization
	Pre-vaccination period	Post-vaccination period
	Average July 2003-June 2007	July 2008-June 2009	July 2009-June 2010
Rotavirus-related AGE
January	69	41	11
February	67	74	58
March	52	55	52
April	24	43	39
May	7	17	10
June	7	8	2
July	9	3	1
August	7	4	0
September	4	3	1
October	5	4	3
November	19	2	3
December	44	21	7
AGE all causes
January	93	51	26
February	89	87	70
March	73	71	62
April	38	60	49
May	25	30	18
June	31	21	15
July	33	13	21
August	37	20	13
September	24	15	14
October	30	32	18
November	38	22	16
December	66	29	21

Note: * Transition period between July 2007 and June 2008 was excluded for this analysis

Figure 2. Monthly hospitalization rates of admissions related to rotavirus gastroenteritis and acute gastroenteritis (AGE) of all causes and in children aged < 5 y