Figures & data
Table 1. Thirteen grass product
Figure 2. Basophil histamin-release in patients treated with four injections of Pollinex Quattro (left) or placebo (right) before and after treatment.Citation19
![Figure 2. Basophil histamin-release in patients treated with four injections of Pollinex Quattro (left) or placebo (right) before and after treatment.Citation19](/cms/asset/3c9b0556-6a55-426d-a0a8-73456ab305c0/khvi_a_10924631_f0002.gif)
Figure 3. Leukotriene levels as a surrogate parameter of inhibiting antibodies before and after immunotherapy.Citation20
![Figure 3. Leukotriene levels as a surrogate parameter of inhibiting antibodies before and after immunotherapy.Citation20](/cms/asset/7bd60da8-4245-461d-ac83-38693898987c/khvi_a_10924631_f0003.gif)
Table 2. Overview of phase 3 clinical studies and post-marketing trials with Pollinex Quattro: study design and key results
Figure 4. Combined Symptom/medication Score in the randomized, placebo-controlled phase 3 study in patients with tree pollen allergy (n = 58).Citation18
![Figure 4. Combined Symptom/medication Score in the randomized, placebo-controlled phase 3 study in patients with tree pollen allergy (n = 58).Citation18](/cms/asset/dd6617f6-8136-40cd-9675-0fc73efe61b1/khvi_a_10924631_f0004.gif)
Figure 5. Proportion of well subjects; i. e. CSMS ≤ 2 during the peak pollen season (a; n = 973) and median number of well days; i.e., patients with a score ≤ 2 and no anti-allergic medication (b; n = 990) in the randomized, placebo-controlled phase 3 study.Citation26
![Figure 5. Proportion of well subjects; i. e. CSMS ≤ 2 during the peak pollen season (a; n = 973) and median number of well days; i.e., patients with a score ≤ 2 and no anti-allergic medication (b; n = 990) in the randomized, placebo-controlled phase 3 study.Citation26](/cms/asset/73835087-5f0c-419a-8809-1ebaff569745/khvi_a_10924631_f0005.gif)
Figure 6. Use of symptomatic medication during therapy in 324 patient completing 3 y of immunization.Citation28
![Figure 6. Use of symptomatic medication during therapy in 324 patient completing 3 y of immunization.Citation28](/cms/asset/da2c68ad-ac62-4b1b-a106-ef23fe081373/khvi_a_10924631_f0006.gif)
Table 3. Summary of local adverse events in clinical trials during the treatment period
Figure 7. Therapy tolerability (a) and acceptance (b) in adults (n = 2,692) and children/adolescents (n = 422).Citation28
![Figure 7. Therapy tolerability (a) and acceptance (b) in adults (n = 2,692) and children/adolescents (n = 422).Citation28](/cms/asset/2fd451fc-979c-4037-b38e-89909010e265/khvi_a_10924631_f0007.gif)