Effectiveness of one dose of mumps vaccine against clinically diagnosed mumps in Guangzhou, China, 2006–2012

Figures & data

Figure 1. Mumps incidence in Guangzhou during 2004–2012 (per 100 000).

Table 1. Demographic characteristics of study subjects

	Number of mumps cases/total (%)	Number of controls/total (%)	P value
Gender			1.000
Male	1294(65.3)	1294(65.3)
Area			1.000
Urban	479(24.2)	479(24.2)
Rural	732(36.9)	732(36.9)
Age of onset^a	4.53 ± 2.42	4.54 ± 2.43	0.943
Vaccinated^b	974(49.1)	1243(62.7)	0.000
Age of vaccination^a,c	1.60 ± 0.76	1.63 ± 0.74	0.262

^aTwo-sample t-test was used to analyze group difference. Mean ± standard deviation. ^bVaccination vs. No vaccination. χ² test was used to analyze group differences. ^cOnly included children received mumps vaccines.

Table 2. Estimates of the effectiveness of one dose mumps vaccination in children 8 mo to 12 y old, multivariate conditional logistic regression analysis

	Vaccinated case (%)	Vaccianted control (%)	Vaccine effectiveness (95%CI),%	P
Vaccination age (months)
8–11	95(75.4)	96(76.2)	98.5(-14734584.4,100.0)	0.610
12–18	443(80.8)	538(83.7)	50.0(-451.4,95.5)	0.571
19–24	315(76.3)	447(86.0)	75.0(33.4,90.6)	0.006
≥ 25	121(13.5)	162(23.3)	64.6(46.0,76.8)	< 0.0001
Time since vaccination (year)
< 1	202(10.2)	269(13.6)	53.6 (37.8,65.4)	< 0.0001
1	221(11.1)	260(13.1)	49.0(28.7,63.5)	< 0.0001
2	150(7.6)	196(9.9)	54.5(34.0,68.6)	< 0.0001
3	101(5.1)	132(6.7)	52.0(27.0, 68.4)	0.001
4	73(3.7)	110(5.5)	62.8(40.3,76.9)	< 0.0001
5	80(4.0)	93(4.7)	56.0(25.0,74.2)	0.003
6	58(2.9)	76(3.8)	57.4(25.9,75.5)	0.002
7	57(2.9)	66(3.3)	52.4(12.8,74.0)	0.016
8	30(1.5)	36(1.8)	52.9(1.2,77.6)	0.046
≥ 9	2(0.1)	5(0.3)	87.7(-18.6,98.7)	0.07
Manufacturer
International	112(5.6)	145(7.3)	51.3(7.2,74.4)	0.029
Domestic	242(12.2)	261(7.3)	21.4(-54.2,59.9)	0.484
Missing	620(31.3)	837(42.2)	57.8(42.1,69.3)	< 0.0001
Total	974(49.1)	1243(62.7)	53.6(41.0,63.5)	< 0.0001