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Transcriptional repression by the Msx1 homeoprotein is associated with global redistribution of the H3K27me3 repressive mark to the nuclear periphery

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Pages 155-161 | Published online: 01 Mar 2012

Figures & data

Figure 1. Msx1 forms a multi-protein complex to regulate target gene expression. The proposed “universal” protein partners are those that Msx1 interacts with in all (or most) cell types; the cell type specific (tissue specific) protein partners are those restricted to distinct biological contexts.

Figure 1. Msx1 forms a multi-protein complex to regulate target gene expression. The proposed “universal” protein partners are those that Msx1 interacts with in all (or most) cell types; the cell type specific (tissue specific) protein partners are those restricted to distinct biological contexts.

Figure 2. Msx1 redistributes the PRC2 complex and H3K27me3 marks to target genes. (A) Gene specific effects. (B) Global redistribution.

Figure 2. Msx1 redistributes the PRC2 complex and H3K27me3 marks to target genes. (A) Gene specific effects. (B) Global redistribution.

Figure 3. Models for how Msx1 recruits PRC2/H3K27me3 to the nuclear periphery.

Figure 3. Models for how Msx1 recruits PRC2/H3K27me3 to the nuclear periphery.

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