OncoImmunology
Volume 2, 2013 - Issue 10
Related Research Data
Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists
Source:
Springer Science and Business Media LLC
Sipuleucel-T immunotherapy for castration-resistant prostate cancer.
Source:
Massachusetts Medical Society
Prognostic and predictive value of the immune infiltrate in cancer
Source:
Informa UK Limited
Peptide vaccines in cancer therapy
Source:
Informa UK Limited
Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
Source:
Springer Science and Business Media LLC
Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis.
Source:
Informa UK Limited
Encounter with antigen-specific primed CD4 T cells promotes MHC class II degradation in dendritic cells
Source:
Proceedings of the National Academy of Sciences
Cancer immunotherapy via dendritic cells
Source:
Springer Vienna
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice.
Source:
American Association for the Advancement of Science (AAAS)
IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses
Source:
Elsevier BV
Antigen processing
Source:
Wiley
Dasatinib in Imatinib-Resistant Philadelphia Chromosome–Positive Leukemias
Source:
Massachusetts Medical Society
Adoptive cell transfer immunotherapy
Source:
Informa UK Limited
A master switch for regulating tolerance and immunity in dendritic cells
Source:
Informa UK Limited
α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial
Source:
Springer Nature
Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity
Source:
Informa UK Limited
Are oncoantigens suitable targets for anti-tumour therapy?
Source:
Springer Science and Business Media LLC
Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity.
Source:
American Association for Cancer Research (AACR)
Folate depletion and antifolate resistance
Source:
Wiley
Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells
Source:
American Society of Hematology
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells
Source:
Springer Science and Business Media LLC
IRF8 mutations and human dendritic-cell immunodeficiency.
Source:
Massachusetts Medical Society
Radiation-induced bystander effects — implications for cancer
Source:
Springer Science and Business Media LLC
HIV-1 infection–induced apoptotic microparticles inhibit human DCs via CD44
Source:
American Society for Clinical Investigation
Immunostimulatory cytokines in cancer therapy
Source:
Informa UK Limited
Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod
Source:
Elsevier BV
Distribution Patterns of Dendritic Cells and T Cells in Diffuse Large B-Cell Lymphomas Correlate with Prognoses
Source:
American Association for Cancer Research (AACR)
Dendritic cells as carriers for a cytotoxic T-lymphocyte epitope-based peptide vaccine in protection against a human papillomavirus type 16-induced tumor.
Source:
Ovid Technologies (Wolters Kluwer Health)
Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 phase I/II trial
Source:
Springer Science and Business Media LLC
Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma.
Source:
Spandidos Publications
Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials
Source:
Springer Science and Business Media LLC
Induction of Dendritic Cell Differentiation by IFN-α in Systemic Lupus Erythematosus
Source:
American Association for the Advancement of Science (AAAS)
An immunosurveillance mechanism controls cancer cell ploidy
Source:
American Association for the Advancement of Science (AAAS)
[Systemic delivery of complexes of melanoma RNA with mannosylated liposomes activates highly efficient murine melanoma-specific cytotoxic T cells in vivo].
Source:
Pleiades Publishing Ltd
Prognostic value of CD208-positive cell infiltration in gastric cancer
Source:
Springer Science and Business Media LLC
Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer
Source:
Informa UK Limited
Mature Dendritic Cells Infiltrate the T Cell-Rich Region of Oral Mucosa in Chronic Periodontitis: In Situ, In Vivo, and In Vitro Studies
Source:
The American Association of Immunologists
Ralph M. Steinman 1943-2011.
Source:
Elsevier BV
Peptide vaccines in cancer therapy
Source:
Informa UK Limited
Plasmacytoid Dendritic Cells Induce Plasma Cell Differentiation through Type I Interferon and Interleukin 6
Source:
Cell Press. Published by Elsevier Inc.
The Cytokines IL-21 and GM-CSF have Opposing Regulatory Roles in the Apoptosis of Conventional Dendritic Cells
Source:
Elsevier Inc.
Dendritic cells loaded with apoptotic tumour cells induce a stronger T-cell response than dendritic cell-tumour hybrids in B-CLL.
Source:
Springer Science and Business Media LLC
Decisions About Dendritic Cells: Past, Present, and Future
Source:
Annual Reviews
Pleurotus ferulae polysaccharides improve the antitumor efficacy of therapeutic human papillomavirus dendritic cell-based vaccine.
Source:
Informa UK Limited
Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells.
Source:
American Society of Hematology
Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia
Source:
Elsevier BV
Enhancement of antigen-presenting capacity and antitumor immunity of dendritic cells pulsed with autologous tumor-derived RNA in mice.
Source:
Ovid Technologies (Wolters Kluwer Health)
Strong emerging rationale for combining oncogene-targeted agents with immunotherapy
Source:
Informa UK Limited
Two Distinct Types of Langerhans Cells Populate the Skin during Steady State and Inflammation
Source:
Elsevier Inc.
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis
Source:
Rockefeller University Press
Ralph Steinman (1943–2011)
Source:
Springer Science and Business Media LLC
Electrofusion of syngeneic dendritic cells and tumor generates potent therapeutic vaccine.
Source:
Elsevier BV
Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells.
Source:
American Society of Hematology
Bone Marrow-Derived Dendritic Cells Serve as Potent Adjuvants for Peptide-Based Antitumor Vaccines
Source:
Oxford University Press (OUP)
Enhanced delivery of immunoliposomes to human dendritic cells by targeting the multilectin receptor DEC-205.
Source:
Elsevier BV
Fusogenic membrane glycoprotein-mediated tumour cell fusion activates human dendritic cells for enhanced IL-12 production and T-cell priming.
Source:
Springer Science and Business Media LLC
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes
Source:
Springer Science and Business Media LLC
Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele
Source:
Elsevier BV
Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma.
Source:
American Society of Hematology
Intratumoral Administration of Dendritic Cells Overexpressing CCL21 Generates Systemic Antitumor Responses and Confers Tumor Immunity
Source:
American Association for Cancer Research (AACR)
ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Source:
American Association for Cancer Research (AACR)
IL-6 switches the differentiation of monocytes from dendritic cells to macrophages
Source:
Springer Science and Business Media LLC
Functional characterization of a STAT3-dependent dendritic cell-derived CD14+ cell population arising upon IL-10-driven maturation
Source:
Informa UK Limited
Targeting dendritic cells in situ for breast cancer immunotherapy.
Source:
Informa UK Limited
Human DC subsets in immune therapy
Source:
Wiley
Prognostic value of HLA-DR expression and dendritic cell infiltration in gastric cancer.
Source:
S. Karger AG
Expansion of Melanoma-specific Cytolytic CD8+ T Cell Precursors in Patients with Metastatic Melanoma Vaccinated with CD34+ Progenitor-derived Dendritic Cells
Source:
Rockefeller University Press
Distinct mechanisms mediate naïve and memory CD8 T-cell tolerance
Source:
Proceedings of the National Academy of Sciences
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
Source:
American Association for Cancer Research (AACR)
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.
Source:
Rockefeller University Press
CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice.
Source:
American Society of Hematology
Therapeutic immune response induced by electrofusion of dendritic and tumor cells.
Source:
Elsevier BV
Dasatinib
Source:
Springer Science and Business Media LLC
Vaccines based on abnormal self-antigens as tumor-associated antigens: immune regulation.
Source:
Elsevier BV
Regression of tumors in mice vaccinated with professional antigen-presenting cells pulsed with tumor extracts.
Source:
Wiley
Sipuleucel-T
Source:
Springer Science and Business Media LLC
Effect of HHP in human tumor cells
Source:
Wiley
IL-10 control of dendritic cells in the skin
Source:
Informa UK Limited
3-Day monocyte-derived dendritic cells stimulated with a combination of OK432, TLR7/8 ligand, and prostaglandin E 2 are a promising alternative for cancer immunotherapy
Source:
Springer Science and Business Media LLC
Induction of Potent Antitumor Immunity by Intratumoral Injection of Interleukin 23–Transduced Dendritic Cells
Source:
American Association for Cancer Research (AACR)
Enhanced immune response to the melanoma antigen gp100 using recombinant adenovirus-transduced dendritic cells.
Source:
Elsevier BV
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia.
Source:
Massachusetts Medical Society
Targeting dendritic cell metabolism in cancer.
Source:
Springer Science and Business Media LLC
Tolerogenic dendritic cells.
Source:
Annual Reviews
Murine Dendritic Cells Pulsed with Whole Tumor Lysates Mediate Potent Antitumor Immune Responses in vitro and in vivo
Source:
Proceedings of the National Academy of Sciences
Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination.
Source:
Mary Ann Liebert Inc
Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity
Source:
Rockefeller University Press
A Randomized Phase II Study of Immunization With Dendritic Cells Modified With Poxvectors Encoding CEA and MUC1 Compared With the Same Poxvectors Plus GM-CSF for Resected Metastatic Colorectal Cancer
Source:
Ovid Technologies (Wolters Kluwer Health)
A new target for cancer vaccines
Source:
Informa UK Limited
Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
Source:
Nature Publishing Group
CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo.
Source:
Rockefeller University Press
C/EBPα is required for development of dendritic cell progenitors
Source:
American Society of Hematology
Efficacy and safety of Id-protein-loaded dendritic cell vaccine in patients with multiple myeloma--phase II study results.
Source:
AEPress, s.r.o.
Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses.
Source:
American Society of Hematology
Immunogenic Cell Death in Cancer Therapy
Source:
Annual Reviews
Taking dendritic cells into medicine
Source:
Springer Science and Business Media LLC
B Subunit of Shiga Toxin-Based Vaccines Synergize with α-Galactosylceramide to Break Tolerance against Self Antigen and Elicit Antiviral Immunity
Source:
The American Association of Immunologists
Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets
Source:
American Society of Hematology
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
Source:
Springer Science and Business Media LLC
Lessons learned from tumor-associated antigens
Source:
Informa UK Limited
Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo.
Source:
Rockefeller University Press
Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?
Source:
American Association for Cancer Research (AACR)
Aldara activates TLR7-independent immune defence
Source:
Nature Publishing Group
Diverse and heritable lineage imprinting of early haematopoietic progenitors
Source:
Springer Science and Business Media LLC
Plasmacytoid dendritic cells promote immunosuppression in ovarian cancer via ICOS costimulation of Foxp3+ T-regulatory cells
Source:
American Association for Cancer Research (AACR)
The expanding family of dendritic cell subsets.
Source:
Springer Science and Business Media LLC
Analysis of NKp30/NCR3 isoforms in untreated HIV-1-infected patients from the ANRS SEROCO cohort.
Source:
Informa UK Limited
DNA vaccines for cancer therapy
Source:
Informa UK Limited
Prognostic Value of Tumor-Infiltrating Dendritic Cells in Colorectal Cancer: Role of Maturation Status and Intratumoral Localization
Source:
American Association for Cancer Research (AACR)
Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells
Source:
Elsevier Inc.
Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity
Source:
American Society of Hematology
Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells
Source:
Rockefeller University Press
How imiquimod licenses plasmacytoid dendritic cells to kill tumors
Source:
Informa UK Limited
Placebo-Controlled Phase III Trial of Immunologic Therapy with Sipuleucel-T (APC8015) in Patients with Metastatic, Asymptomatic Hormone Refractory Prostate Cancer
Source:
American Society of Clinical Oncology (ASCO)
Identification of human inflammatory dendritic cells.
Source:
Informa UK Limited
Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution.
Source:
Rockefeller University Press
Programming human dendritic cells with mRNA.
Source:
Humana Press
Efficient nonviral transfection of dendritic cells and their use for in vivo immunization.
Source:
Springer Science and Business Media LLC
Trial watch: IDO inhibitors in cancer therapy
Source:
Informa UK Limited
Dendritic cell infiltration and prognosis of human hepatocellular carcinoma
Source:
Springer Science and Business Media LLC
Cardiac glycosides and cancer therapy
Source:
Informa UK Limited
Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists.
Source:
Springer Science and Business Media LLC
The present status and future prospects of peptide-based cancer vaccines.
Source:
Oxford University Press (OUP)
Immunoglobulins drive terminal maturation of splenic dendritic cells
Source:
Proceedings of the National Academy of Sciences
Mitochondria: master regulators of danger signalling
Source:
Springer Science and Business Media LLC
Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement
Source:
Elsevier BV
The contribution of immune responses to the efficacy of radiotherapy
Source:
Informa UK Limited
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Source:
Elsevier BV
Prediction of sites of recurrence in gastric carcinoma using immunohistochemical parameters.
Source:
Wiley
Glycyrrhiza uralensis water extract enhances dendritic cell maturation and antitumor efficacy of HPV dendritic cell-based vaccine.
Source:
Springer Science and Business Media LLC
Cancer Immunology
Source:
Massachusetts Medical Society
Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors.
Source:
Informa UK Limited
Natural type I interferon-producing cells as a link between innate and adaptive immunity.
Source:
Elsevier BV
Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient.
Source:
Springer Science and Business Media LLC
Eradication of Large Tumors in Mice by a Tritherapy Targeting the Innate, Adaptive, and Regulatory Components of the Immune System
Source:
American Association for Cancer Research (AACR)
Immunostimulatory cytokines
Source:
Informa UK Limited
Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage
Source:
Rockefeller University Press
DC Vaccine Eliminates HER-2 Expression
Source:
Wiley
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27–CD70 pathway
Source:
Rockefeller University Press
Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines
Source:
Informa UK Limited
Targeting dendritic cells—why bother?
Source:
American Society of Hematology
Electrofusion of a weakly immunogenic neuroblastoma with dendritic cells produces a tumor vaccine.
Source:
Elsevier BV
Radiation-induced bystander signalling in cancer therapy
Source:
Springer Science and Business Media LLC
Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy
Source:
Informa UK Limited
Comparative Analysis of Genetically Modified Dendritic Cells and Tumor Cells as Therapeutic Cancer Vaccines
Source:
Rockefeller University Press
Cancer vaccines: between the idea and the reality.
Source:
Springer Science and Business Media LLC
How quantitative differences in dendritic cell maturation can direct TH1/TH2-cell polarization
Source:
Informa UK Limited
Peptide-Based Anticancer Vaccines: Recent Advances and Future Perspectives
Source:
Bentham Science Publishers Ltd.
Is Tumor Immunity the Same Thing As Autoimmunity? Implications for Cancer Immunotherapy
Source:
American Society of Clinical Oncology (ASCO)
Designing Tomorrow's Vaccines
Source:
Massachusetts Medical Society
Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses.
Source:
The American Association of Immunologists
Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies
Source:
Springer Science and Business Media LLC
Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures
Source:
American Society of Clinical Oncology (ASCO)
Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer
Source:
Springer Science and Business Media LLC
NKT cell adjuvants in therapeutic vaccines against hematological cancers.
Source:
Informa UK Limited
Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.
Source:
Rockefeller University Press
Plasmacytoid dendritic cells and their therapeutic activity in cancer
Source:
Informa UK Limited
Ralph M. Steinman (1943–2011)
Source:
American Association for the Advancement of Science (AAAS)
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain
Source:
Rockefeller University Press
Efficient genetic modification of murine dendritic cells by electroporation with mRNA.
Source:
Springer Science and Business Media LLC
Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming.
Source:
Proceedings of the National Academy of Sciences
CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth
Source:
American Association for Cancer Research (AACR)
Human dendritic cell subsets in vaccination.
Source:
Elsevier BV
Adoptive cell transfer for anticancer immunotherapy
Source:
Informa UK Limited
Dendritic cell–tumor cell hybrids and immunotherapy: what's next?
Source:
Elsevier BV
Phenotypic and Functional Analysis of Dendritic Cells and Clinical Outcome in Patients With High-Risk Melanoma Treated With Adjuvant Granulocyte Macrophage Colony-Stimulating Factor
Source:
American Society of Clinical Oncology (ASCO)
Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
Source:
Proceedings of the National Academy of Sciences
Tumor microenvironment is multifaceted.
Source:
Springer Science and Business Media LLC
Cancer Immunotherapy: A Treatment for the Masses
Source:
American Association for the Advancement of Science (AAAS)
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