Figures & data
Figure 1 Schematic representation of the model/experiment cycle and the potential of multiscale validation via multiscale modeling. The process is iterative and hypothesis driven.
Figure 2 A simple scale separation map for the process of in-stent restenosis. The initial event (injury to the blood vessel wall) leads to smooth muscle cell (SMC) hyperplasia. Muscle cell growth and migration is modified by the action of a drug or by changes in wall shear stress associated with blood flow. The solid arrows indicate the coupling between different scale models, the dotted arrows are the inputs to the model.
