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Heterogeneous seeding of HET-s(218–289) and the mutability of prion structures

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Pages 178-182 | Received 11 Dec 2013, Accepted 05 Feb 2014, Published online: 18 Feb 2014

Figures & data

Figure 1. Structural models of HET-s(218–289) polymorphs. (A) Two-rung β-solenoid (PDB ID: 2KJ3). (B) Hypothetical stacked β-sheet model.Citation21

Figure 1. Structural models of HET-s(218–289) polymorphs. (A) Two-rung β-solenoid (PDB ID: 2KJ3). (B) Hypothetical stacked β-sheet model.Citation21

Figure 2. X-ray fiber diffraction patterns of HET-s(218–289) and PrP. (A) Stacked β-sheet HET-s(218–289). (B) β-solenoid HET-s(218–289). (C) rec PrP (90–231). (D) Brain-derived PrP 27–30 (strain Sc237), inset has intensity adjusted to show low-angle intensity maxima.

Figure 2. X-ray fiber diffraction patterns of HET-s(218–289) and PrP. (A) Stacked β-sheet HET-s(218–289). (B) β-solenoid HET-s(218–289). (C) rec PrP (90–231). (D) Brain-derived PrP 27–30 (strain Sc237), inset has intensity adjusted to show low-angle intensity maxima.

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