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Addendum

Unfolded protein response, treatment and CMT1B

, &
Article: e24049 | Received 11 Feb 2013, Accepted 19 Feb 2013, Published online: 20 Feb 2013

Figures & data

Figure 1. Model of PCC and CO effects on R98C Schwann cells. We propose that PCC or CO treatment promotes a myelinating phenotype in Schwann cells by decreasing the expression of transcription factors c-Jun or SCIP that inhibit myelination when upregulated.

Figure 1. Model of PCC and CO effects on R98C Schwann cells. We propose that PCC or CO treatment promotes a myelinating phenotype in Schwann cells by decreasing the expression of transcription factors c-Jun or SCIP that inhibit myelination when upregulated.