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ACTA REVIEW

The role of C-reactive protein in modern obstetric and gynecological practice

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Pages 394-401 | Received 10 Jan 2005, Published online: 03 Aug 2009
 

Abstract

C-reactive protein is an acute phase protein widely used as an indicator of infectious or inflammatory conditions. Traditionally it has been used as an adjunctive test for inflammation and as a marker of disease activity. Though sensitive, its nonspecific nature imposes limitation on its clinical use. Currently C-reactive protein is used in the management of chorioamnionitis, preterm premature rupture of membranes, pelvic inflammatory disease, and urinary tract infection. Interestingly, several obstetric conditions such as pre-eclampsia and gestational diabetes are now known to have an underlying inflammatory basis and there is an emerging role of C-reactive protein testing in managing these diseases. Additionally C-reactive protein testing has an established place in management of several acute abdominal conditions. The aim of this paper is to review the place of C-reactive protein in modern obstetric and gynecological practice.

Acronyms
CRP=

C-reactive protein

IL=

interleukin

ESR=

erythrocyte sedimentation rate

CA=

chorioamnionitis

PPROM=

preterm premature rupture of membranes

PL=

preterm labor

WBC=

white blood cell count

PID=

pelvic inflammatory disease

UTI=

urinary tract infection

BMI=

body mass index

HRT=

hormonal replacement therapy

Acronyms
CRP=

C-reactive protein

IL=

interleukin

ESR=

erythrocyte sedimentation rate

CA=

chorioamnionitis

PPROM=

preterm premature rupture of membranes

PL=

preterm labor

WBC=

white blood cell count

PID=

pelvic inflammatory disease

UTI=

urinary tract infection

BMI=

body mass index

HRT=

hormonal replacement therapy

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