Evaluation of peri-implant crevicular fluid prostaglandin E₂ levels in augmented extraction sockets by different biomaterials

Abstract

Objectives: This study compares peri-implant crevicular fluid (PICF) prostaglandin E₂ (PGE₂) levels, clinical parameters and implant stability quotient (ISQ) values around implants placed in augmented extraction sockets.

Materials and methods: The sockets (24 in total) were randomly augmented using either EMD or Bio-Oss Collagen. Implant placements were performed after three months of healing. ISQ readings were evaluated at three points: at the time of surgery, at the first month and at the third month. PICF was collected for PGE₂ evaluation after the first and the third months of implant surgery.

Results: After the first month, a higher level of PICF PGE₂ was observed in the EMD group than in the Bio-Oss Collagen group, and this increase was of statistical significance; however, at the third month there was no statistically significant difference in PICF PGE₂ levels between the two groups. For implants placed in EMD sites, ISQ values were statistically higher at the third month than at the first month, while no significant differences in ISQ value were detected between the first and third months in Bio-Oss Collagen sites.

Conclusions: The results of this research suggest that both EMD and Bio-Oss Collagen are effective treatment modalities for stimulating the formation of new bone at extraction sites prior to implant surgery.

Keywords:

• Extraction sockets
• augmentation
• prostoglandin E2
• peri-implant crevicular fluid

Disclosure statement

The authors declare that they have no conflict of interest.

Funding

This study was financially supported by Gazi University Research Foundation’s Scientific Research Project Support (03-2007-20).

Notes on contributors

Eylem Ayhan Alkan is an assistant professor in the Department of Periodontology, Yüzüncü Y?l University, Faculty of Dentistry, Van. Previously, she worked at Gazi University. Her research is focused on in the field of periodontology.

Gülay Tüter is a professor in the Department of Periodontology, Gazi University, Faculty of Dentistry, Ankara. Her research and clinical interests focus mainly on periodontal pathogenesis, influence of systemic diseases on periodontal health, host modulation therapy and advance dental implant surgeries. She worked at different universities such as Helsinki University, Faculty of Dentistry, Department of Periodontology and State University of New York, Faculty of Dentistry, Department of Periodontology, before.

Ateş Parlar previously, was a professor of Department of Periodontology, Gazi University, Faculty of Dentistry, Ankara. He works in his private dental office.

Ayşegül Yücel is a professor in the Department of Immunology, Gazi University, Faculty of Medicine, Ankara. Her research is focused on in the field of immunology.

Bülent Kurtiş a professor in the Department of Periodontology, Gazi University, Faculty of Dentistry, Ankara. His research is focused on in the field of periodontology.