Abstract
Objective: This study was performed to determine the volume distribution of EH in contralateral DEH.
Patients and methods: Five contralateral DEH patients (age range = 21–77 years) and one ipsilateral DEH patient. Visualization of in vivo EH using 3T magnetic resonance (MR) imaging was performed by intravenous administration of gadolinium. The EH volume was determined quantitatively by adding the area of EH in consecutive MR images.
Results: The total EH volume of the patients with contralateral DEH varied from 24.2 to 56.6 μL in the first ear and 20.2 to 35.7 μL in the contralateral ear. EH was dominantly developed in the first ear for Patient no. 3 and 4, and not dominantly developed in the first ear for Patient no. 1, 2, and 5.
Conclusions: The volume distribution of endolymphatic hydrops (EH) in contralateral delayed endolymphatic hydrops (DEH) was classified into two phenotypes. This suggests that contralateral DEH may consist of two etiologies.
Chinese abstract
目的:本研究的目的是确定对侧DEH中EH的体积分布。
患者和方法:5例对侧DEH患者(年龄范围= 21-77岁)和1例同侧DEH患者。 使用3T磁共振(MR)成像, 通过静脉注射钆, 进行体内EH观测。 通过在连续MR图像中添加EH的面积来定量确定EH体积。
结果:对侧DEH患者的总EH体积在第一耳中为24.2〜56.6μL, 对侧耳为20.2〜35.7μL。 EH主要发展于第三、第四位患者的第一耳朵, 并没有主要发展于第一、第二和第五位患者的第一个耳朵。
结论:对侧延迟内淋巴积水(DEH)中内淋巴积水(EH)的体积分布分为两种表型。 这表明对侧DEH可能有两种病因。
Acknowledgements
This research was supported partially by the medical research fund of the Hyogo Medical Association and partially by a Grant-in-Aid for Research on Intractable Vestibular Disorder from Japan Agency of Medical Research and Development and the Ministry of a Health, Labor and Welfare of Japan.
Disclosure statement
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.