Abstract
Background: To explore the relationship between the morphological characteristics and pathological diagnosis of vocal cords leukoplakia.
Methods: A total of 1635 vocal cords were collected. The morphology were classified into three types (Type I, II, III): flat and smooth; bulge and smooth; bulge and rough. The pathological reports were classified into five groups: no dysplasia, mild dysplasia, moderate dysplasia, severe dysplasia and cancerization. The number of the patients or vocal cords in each type and group was counted and their ratio was compared.
Results: In Type I, the number of vocal cord in Group A group was 2.2 and 2.6 times of the one in Type II and Type III respectively. In Type II, the mild, moderate dysplasia ratio was higher than those in Type I. In Type III group the ratio of severe dysplasia was 2.6 and 5.5 times of the one in Type II and Type I respectively. The ratio of Group E in Type III was 2.7 and 7.9 times of the one of Type II and Type I. The result was significant (pearson Chi-square value was 517.6, p = .00).
Conclusions: The pathological results of vocal cord leukoplakia can be evaluated by morphology in most cases.
Chinese abstract
结论:大多数情况下可以通过形态学评估声带白斑病理结果。
背景:探讨声带白斑的形态特征与病理诊断之间的关系。
方法:收集共1635条声带。形态分为三类(I型、II型、III型):平滑、凸起平滑、凸起粗糙。病理报告分为5组:无发育不良、轻度发育不良、中度发育不良、严重发育不良和癌变。对每个类型和组中的患者数或声带数进行计数, 并比较其比例。
结果:I型中, A组声带数分别为Ⅱ型和Ⅲ型的2.2倍和2.6倍。在Ⅱ型中, 轻度和中度发育不良比例高于I型。在III型组中, 严重发育不良的比例分别为II型和I型的2.6倍和5.5倍。 Ⅲ型中, E组比例分别为Ⅱ型和Ⅰ型的2.7倍和7.9倍。其结果显著(Pearson卡方值为517.6, p = 0 .00)。
Acknowledgements
The authors thank Yogun Thungavelu for revising this manuscript.
Disclosure statement
The authors report no conflicts of interest to disclose. The authors alone are responsible for the content and writing of the paper.