Complications in translabyrinthine surgery of vestibular schwannoma

Abstract

Objective: To evaluate the risk of complications associated with tumor size and patient’s age in translabyrinthine vestibular schwannoma surgery.

Methods: 700 patients with vestibular schwannoma primarily underwent translabyrinthine surgery between 1988 and 2014. Pre- and postoperative data were collected in a database and incidence of the postoperative complications cerebrospinal fluid leakage, meningitis, intracranial hemorrhage (ICH), facial nerve function and mortality were assessed and related to the tumor size and patient’s age and retrospectively evaluated.

Results: The tumor size significantly influenced the incidence of ICH and facial nerve dysfunction whereas age was correlated to facial nerve outcome.

Conclusions: The translabyrinthine approach is a safe surgical procedure with relatively low risks of complications. The tumor size was significantly associated with a higher risk of ICH and facial nerve dysfunction whereas age only influenced the facial nerve outcome.

Chinese abstract

目的：评估经迷路前庭神经鞘瘤手术中与肿瘤大小和患者年龄相关的并发症的风险。

方法： 1988〜2014年间700例前庭神经鞘瘤患者进行了迷路手术。从资料库收集了术前和术后资料, 检查了脑脊液漏、脑膜炎、颅内出血（ICH）、面神经功能、死亡率等术后并发症, 并将其与肿瘤大小和患者年龄相联系。

结果：肿瘤大小显著影响ICH和面神经功能障碍的发生率, 而年龄与面神经结果相关。

结论：经迷路法是一种安全的手术方式, 并发症风险相对较低。肿瘤大小与ICH和面神经功能障碍的风险显著相关, 而年龄仅影响面神经结果。

Keywords:

• Translabyrinthine surgery
• complications
• tumor size
• age

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This study was supported by the Uppsala University Hospital ALF Grants.