http://orcid.org/0000-0003-1430-1675
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Abstract
Background: There are some debates regarding the benefit from cochlear implantation (CI) for prelingually deaf children with white matter changes.
Objective: To assess the hearing and speech outcomes of prelingually deaf children with white matter changes (group A), and those with complete deafness (group B), at 2 years after CI.
Material and Methods: Study 1 included 32 and 34 children in group A and B, respectively. The Categories of Auditory Performance (CAP) and Speech Intelligibility Rate (SIR) were used to assess the performance on hearing and speech. Study 2 included eight children with white matter changes and eight with complete deafness at 2 years post-CI, and nine normal-hearing peers. The mismatch response (MMR) to the stimulus pair ‘ba’/‘pa’ was investigated.
Results: There was no significant difference on CAP or SIR scores between the children in group A and B. All children with white matter changes showed MMRs to Mandarin consonants at 2 years post-CI. And there was no significant difference on the incidence, the latency or amplitude of MMR among three groups.
Conclusions and significance: Most prelingually deaf children with white matter changes got good outcomes from CI. CI is not a contraindication for most individuals with white matter changes.
Chinese abstract
背景：关于对患有白质改变的语言前聋儿进行人工耳蜗植入（CI）的益处, 存在一些争论。
目的：评估CI后2年内患有白质改变的语言前聋儿（A组）和完全耳聋的儿童（B组）的听觉和言语结果。
材料和方法：研究1包括A组和B组, 分别由32和34名儿童组成。听觉表现（CAP）和语音清晰度（SIR）的类别用于评估听力和语言表现。研究2包括8名有白质变化的儿童和8名在CI 2年后完全性耳聋的儿童, 以及9名听力正常的同龄儿童。研究了对刺激对“ ba” /“ pa”的失配响应（MMR）。
结果：A组和B组的孩子在CAP或SIR评分上没有显著差异。所有有白质变化的孩子在CI后2年都表现出对普通话辅音的MMR。三组之间MMR的发生率、潜伏期或幅度均无显著差异。
结论和意义：大多数白质改变的语言前聋儿由于CI而获得了良好的效果。对于大多数有白质变化的人来说, 不必禁忌CI。
Disclosure statement
No potential conflict of interest was reported by the authors.