Effects of endolymphatic sac decompression combined with posterior tympanotomy with local steroids for intractable Meniere’s disease

Abstract

Background: Endolymphatic sac decompression surgery (ESDS) is commonly used for intractable Meniere’s disease, but its effect remains controversial because of the low rate of vertigo control.

Objectives: In the present study, we examined ESDS combined with posterior tympanotomy with local steroids as a new therapeutic strategy for intractable Meniere’s disease.

Materials and methods: This retrospective study enrolled 19 patients with Meniere’s disease using ESDS combined with posterior tympanotomy with local steroids between 2015 and 2018. Postoperatively we recorded and evaluated changes in vertigo attack frequency and hearing level.

Results: Vertigo episodes decreased from 3.6 ± 3.2 times preoperatively to 0.2 ± 0.5 times postoperatively, with 89.5% complete vertigo control rate. Mean PTA decreased from 40.5 ± 21.3 dB to 39.5 ± 17.5 dB postoperatively, with 21.1% improvement rate.

Conclusions and significance: The present findings suggest that ESDS combined with posterior tympanotomy with local steroids could improve clinical results of hearing as well as vertigo control for intractable Meniere’s disease.

Chinese abstract

背景：内淋巴囊减压术（ESDS）是治疗难治性梅尼埃病的常用方法, 但由于其眩晕控制率低, 其疗效仍存在争议。

目的：本研究探讨一种治疗难治性梅尼埃病的新方法, 即综合ESDS和施用局部类固醇的后鼓室切开术。

材料与方法：本回顾性研究包括2015-2018年间收治的19例梅尼埃病患者, 均采用ESDS和施用局部类固醇的后鼓室切开术的综合疗法。术后我们记录并评估眩晕发作频率和听力水平的变化。

结果：眩晕发作次数由术前的3.6 ± 3.2次降至术后的0.2 ± 0.5次, 完全眩晕控制率为89.5%。术后平均PTA由40.5±21.3dB降至39.5±17.5dB, 改善率为21.1%。

结论及意义：ESDS和施用局部类固醇的后鼓室切开术的综合疗法治疗顽固性梅尼埃病可提高听力和眩晕的临床疗效。

Keywords:

• Meniere’s disease
• endolymphatic sac decompression
• local steroids

Disclosure statement

No potential conflict of interest was reported by the authors.