Abstract
Introduction: The subjective visual vertical (SVV) is the most frequently assessed modality of verticality perception and has been measured in a variety of clinical situations, including peripheral vestibular lesions.
Aim: The main objectives are (1) to collect normative data of Virtual SVV™ from healthy subjects, and (2) to study the correlation between Virtual SVV™ and ocular vestibular-evoked myogenic potentials (o-VEMP) on healthy subjects.
Materials and methods: Forty-three healthy subjects were recruited. Air conduction (AC)-elicited oVEMPs and bone conduction (BC)-elicited oVEMPs were measured. BC stimuli were produced with a RadioEar B-81 High Output Bone Transducer. Virtual SVV™ were also measured.
Results: Virtual SVV™ data from our healthy subjects were consistent with previously published normative SVV data. Normal Virtual SVV™ data did not correlate with normal AC-elicited and BC-elicited oVEMPs.
Conclusions: Virtual SVV™ data from our healthy subjects were consistent with previously published normative SVV data. Virtual SVV™ data from our 43 health subjects only had weak correlation with c-VEMP, AC-elicited and BC-elicited oVEMPs. These data serve as a baseline for a future study of patients with unilateral utricular dysfunction.
Significance: The Virtual SVV™ can be an attractive substitute for traditional SVV in clinical settings.
Chinese abstract
导言:主观视觉垂直(SVV)是最常被检测的垂直知觉形式, 并已在各种临床情况下被测量, 包括外围前庭病变。
目的:(1)收集健康人虚拟SVV™的标准资料;(2)研究虚拟SVV™与健康人眼前庭诱发肌源性电位(o-VEMP)的相关性。
材料与方法:选取43名健康受试者。测量空气传导(AC)诱发的oVEMPs和骨传导(BC)诱发的oVEMPs。用放射耳B-81高输出骨传感器产生BC刺激。还测量了虚拟SVV™。
结果:来自健康受试者的虚拟SVV™数据与以前公布的标准SVV数据一致。正常虚拟SVV™数据与正常AC诱发和BC诱发的oVEMPs无关。
结论:来自健康受试者的虚拟SVV™数据与以前公布的标准SVV数据一致。43名健康受试者的虚拟SVV™数据仅与c-VEMP、AC诱发和BC诱发的oVEMPs呈弱相关。这些数据可作为未来研究单侧泡囊功能障碍患者的基线。
意义:虚拟SVV™可以在临床上替代传统的SVV。
Acknowledgements
Authors thank Caroline P.E. Price, B.S. (NU) for study coordination, obtaining consents, and IRB regulatory work and Drs. Sumitrajit Dhar and Kristine Riley for mentorship in Capstone project.