The effect of obstructive sleep apnea surgery on laryngopharyngeal reflux with obstructive sleep apnea

Abstract

Background: Obstructive sleep apnea (OSA) may play a role in the occurrence of laryngopharyngeal reflux (LPR). OSA surgery also may have a significant curative effect on LPR with OSA.

Objectives: To analyze the role of OSA in LPR and the effect of OSA surgery on LPR with OSA.

Methods: Forty-five OSA patients with LPR symptoms were enrolled and were divided into the LPR positive group (RSI > 13) and the LPR suspicious group (1 ≤ RSI ≤ 13) based on reflux symptom index (RSI). All the patients underwent OSA surgery. The RSI scores at three different time points postoperatively were compared with that preoperatively.

Results: In the LPR positive and LPR suspicious group, the result revealed that there were significant differences in RSI score between one month, three months, six months after surgery and before surgery (p < .001 for all). Moreover, in the LPR positive group, there was a significant difference in RSI score among one month, three months and six months after surgery (p = .01).

Conclusions and significance: The effect of OSA on LPR exists and OSA surgery can improve the symptoms of LPR with OSA obviously. For some LPR patients with OSA, the combination therapy of OSA and LPR is needed.

Chinese abstract

背景：阻塞性睡眠呼吸暂停（OSA）可能对喉咽反流（LPR）的发生起一定的作用。 OSA手术对OSA导致的LPR也可能具有显著疗效。

目的：分析OSA对LPR发生的作用以及OSA手术对由OSA导致的LPR的影响。

方法：招纳45名具有LPR症状的OSA患者, 根据反流症状指数（RSI）将其分为LPR阳性组（RSI> 13）和LPR疑症组（1< RSI< 13）。所有患者均接受了OSA手术。将术后三个不同时间点的RSI得分与术前进行比较。

结果：结果显示, 在LPR阳性组和LPR疑症组中, 手术后1个月、3个月、6个月的RSI评分与手术之前的RSI评分存在显著差异（P＜0.001）。此外, 在LPR阳性组中, 术后1个月、3个月和6个月的RSI评分之间存在显著差异（p 1⁄4 .01）。

结论和意义：OSA对LPR的发生起的作用是存在的, 并且OSA手术可以明显改善OSA导致的LPR的症状。对于一些患有OSA的LPR患者, 需要进行OSA和LPR的联合治疗。

Keywords:

• Obstructive sleep apnea
• surgery
• laryngopharyngeal reflux

Disclosure statement

No potential conflict of interest was reported by the author(s).