Abstract
Background
There has been no report on the predictive value of auditory steady-state response (ASSR) in the hearing prognosis of sudden sensorineural hearing loss (SSNHL).
Aims/objectives
To investigate whether ASSR can be a prognostic indicator of hearing outcome in patients with SSNHL after systemic steroid treatment.
Material and methods
Fifty-three patients with unilateral mild to severe SSNHL (≤90 dB HL at 0.5k, 1k, 2k, and 4 kHz, 4FA) were included. All patients received systemic high dose steroid therapy within one month after onset. The difference between the threshold levels measured by ASSR and PTA on the same day [ASSR – PTA] was calculated. The hearing recovery (HR) was defined as a < 30 dB HL of final degree of hearing loss and a > 15 dB HL of hearing gain.
Results
The HR (+) group showed significantly worse ASSR predicted threshold than pure-tone threshold in univariate (t(51) = 2.412, p = .020) and multivariate analysis (OR 0.910, p = .012). The [ASSR – PTA] threshold showed significantly moderate correlation with hearing gain (r = −0.303, p = .028).
Conclusions
Worse ASSR predicted threshold than pure-tone threshold predicted poor hearing outcome after systemic steroid treatment in mild to severe unilateral SSNHL.
Chinese abstract
背景:目前尚无关于听觉稳态反应(ASSR)对突发性感音神经性听力损失(SSNHL)患者的听力预测价值的报道。
目的:研究SSR是否可以作为经全身性激素治疗后的SSNHL患者的听力预后指标。材料和方法:包括了53例单侧轻度至重度SSNHL(在0.5、1、2和4 kHz时, 90 dB HL, 4FA)的患者。所有患者在发病后一个月内均接受全身高剂量类固醇治疗。计算了当天由ASSR和PTA测量的阈值水平之间的差异[ASSR – PTA]。听力恢复(HR)定义为最终听力损失度<30 dB HL和听力增益> 15 dB HL。
结果:在单变量(t(51)¼2.412, p¼.020)和多变量分析(OR 0.910, p¼.012)中, HR(þ)组的ASSR预测阈值明显比纯音阈值差。 [ASSR – PTA]阈值显示出与听力增益的显著中度相关性(r¼0.303, p¼.028)。
结论:对于轻度至重度单侧SSNHL患者, 在接受系统激素治疗后, ASSR预测阈值较纯音阈值预测的听力结果差。
Disclosure statement
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.