Abstract
Background
Although various medical remedies have been attempted to alleviate the symptoms of Meniere’s disease (MD), the risk–benefit ratios of these various treatments remain debatable.
Objective
We investigated the efficacy of sound stimulation of 100 Hz for treating vestibular dysfunction in patients with Meniere’s disease (MD).
Materials and methods
Patients with definitive MD with intractable vestibular symptoms and endolymphatic hydrops (EH) in the inner ear were evaluated. The experimental group received sound stimulation of 75 dB at a frequency of 100 Hz for 5 min, and the control group received sound stimulation of 75 dB at a frequency of 250 Hz for 5 min. Cervical vestibular-evoked myogenic potentials (cVEMPs) were measured before and after each sound stimulation, and the results of the clinical tests were compared between the two patient groups.
Results
Significant increases in cVEMP amplitudes were observed after sound stimulation of 100 Hz in ears with vestibular endolymphatic hydrops, although no such improvement was observed in the control group.
Conclusion
Sound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cVEMP amplitude in patients with definitive MD. Adequate sound stimulation might be a new method for treating vestibular dysfunction associated with MD.
Chinese Abstract
背景
慢性中耳炎 (COM) 等炎症性疾病可能会导致砧骨微结构和功能的不可逆转的损害, 随后导致传导性听力损失。
目的
通过有或无砧骨-镫骨关节间断 (ISJD) 的 COM 患者的术前颞部 CT, 研究砧骨体 (IB) 和长突 (ILP) 的骨矿物质密度 (BMD), 并确定ISJD 组群中 BMD 值与术后气骨间隙 (ABG) 之间的相关性。
材料和方法
比较有和无 ISJD 患者之间的平均IB密度(IBD)/枕骨密度(OBD)和ILP密度(ILPD)/ OBD 的值。 评估 ISJD 组中ABG 增益和术前砧骨密度值之间的相关性。
结果
ISJ 完整的患者的平均 IBD/OBD 和 ILPD/OBD 值显著较高。ISJD 群组中, 术后 ABG 增益与 ILPD/OBD 值呈中度正相关。
结论及意义
ISJD患者的砧骨BMD下降可能与ILP和IB有关, 是由 COM 中 ILP 裂解引起的。 对于患有 ISJD 的 COM 患者, 术前较高的 ILPD/OBD值与术后较高的ABG 增益相关。
Disclosure statement
No potential conflict of interest was reported by the author(s).