New Analytical Techniques for the Detection of BSE and other TSEs

Abstract

This review discusses new methods for detecting BSE and other TSE prions. A number of different analytical techniques have been applied in the past few years. New immunoassays (as well as new antibodies), an improved Western blot, CE-based methods, and a Raman-based method are some of the analytical techniques reviewed. In addition, methods to increase the concentration of prions and some cautionary notes are presented in this review.

Keywords:

• BSE
• TSE
• immunoassay
• prion
• CE
• Raman
• Western blot
• antibodies
• diagnostic methods

Acknowledgments

ANOVA was performed utilizing JMP 5.1.1 (www.jmp.com). The author of this paper does not have any financial ties to any of the companies mentioned in the paper.