Electrochemical Biosensors for Sequence‐Specific DNA Detection

Abstract

This review summarizes the most relevant work performed in the last years in the field of the DNA-based electrochemical biosensors for sequence-specific DNA detection. The approaches used for preparing the biosensing layer, as well as the schemes developed for the transduction of the hybridization event are also discussed.

Keywords:

• DNA biosensors
• hybridization
• electrochemical detection
• nucleic acids
• sequence-specific detection
• DNA immobilization
• redox indicators
• amplification

Acknowledgments

The authors are grateful to Fundación Antorchas, CONICET, ANPCyT, SECyT‐UNC and ABC for the financial support of their research activities. M. L. Pedano acknowledges CONICET for the fellowship received.