Abstract
This article describes the development and validation of a quantitative analytical method for determination of estradiol in several pharmaceutical products (powder, tablets, cream, solutions for injection) using UV-vis molecular absorption spectrometry. The proposed method is accurate, precise, sensitive, and selective and can be used in quality control laboratories.
Notes
Notes. Sample 1: 0.5 mL estradiol stock solution + 5 ml EtOH + NaOH 0.1 N to 50 mL volumetric flask. Sample 2: 3.0 mL estradiol stock solution + 5 ml EtOH + NaOH 0.1 N to 50 mL volumetric flask. Sample 3: 7.0 mL estradiol stock solution + 5 ml EtOH + NaOH 0.1 N to 50 mL volumetric flask.