Abstract
A fast potentiometric determination method has been reported for pentazocine in human plasma without complicated pretreatments using a coated-wire potentiometric selective electrode. The sensing membrane was made by incorporating of ion-association complexes of pentazocine cation and sodium tetraphenyl borate (NaTPB) in a polyvinyl chloride. The sensor exhibited fast, stable, and linear Nernstian response over the range of 5 × 10−5 to 0.1 mol L−1 pentazocine with a slope of 57.8 mV per decade and with detection limit of 3.2 × 10−5 mol L−1. The proposed sensor has been used for determination of pentazocine in human plasma and urine.
Acknowledgments
The authors express their appreciation to the Isfahan University of Technology Research Councils and Center of Excellence in Sensors for financial support of this work.
Notes
*Dibutyl phthalate (DBP); Dioctyl phthalate (DOP); 2-Nitrophenyloctylether (NPOE); Dioctylsebacate (DOS).
a Shows the standard deviation for three-replicate analysis.