Automated Determination of Captopril by Flow and Sequential Injection Analysis: A Review

Abstract

The present study intends to present a review of automated methods for the determination of Captopril—an angiotensin converting enzyme (ACE) inhibitor—using flow or sequential injection analysis. The review covers a range of more than fifteen years of published research on this topic (1993–today). The methods are classified according to the detection systems in three categories, namely spectrophotometric, chemiluminescence, and electroanalytical. The principles and main analytical figures of merit of the reported studies are presented and discussed.

Keywords:

• Captopril
• Determination
• Flow injection analysis
• Review
• Sequential injection analysis

Acknowledgments

This paper was submitted as part of a Special Issue on Flow Injection Analysis.

Notes

¹MP-FI: Multi-pumping Flow Injection.

²r-FI: Reversed Flow Injection.