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Analytical Letters Volume 44, 2011 - Issue 12
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EDUCATION

Mini Review: Determination of Sildenafil Citrate in Pharmaceutical Prepaprations

Andrei A. Bunaciu SC HOFIGAL SA, Analytical Research Department, Bucharest, Romania
,
Rasha M. El Nashar Faculty of Pharmacy and Biotechnology, Pharmaceutical Chemistry Department, German University in Cairo, Cairo, Egypt; Faculty of Science, Chemistry Department, Cairo University, Giza
&
Hassan Y. Aboul-Enein Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, Cairo, EgyptCorrespondence[email protected]
Pages 2085-2093 | Received 15 Apr 2010, Accepted 18 Aug 2010, Published online: 12 Aug 2011
 
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Abstract

Sildenafil citrate (SC) is a commonly used pharmaceutical compound in the treatment of erectile dysfunction. Many side effects were reported for overdose including: headaches; fainting resulting from dilation of blood vessels, and blue-tinted vision. Many analytical methods are reported in literature for the assay of sildenafil citrate in its generic form or pharmaceutical formulations; these will be summarized in the present mini review.

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