A Nonenzymatic Glucose Sensor Based on a Copper Nanoparticle–Zinc Oxide Nanorod Array

Abstract

A non-enzymatic sensor for glucose based on copper nanoparticles and zinc oxide nanorod array modified fluorine-doped tin oxide conductive glass electrode was constructed by two-step electrodeposition. The electrode was characterized by scanning electron microscopy and X-ray diffraction. The electrochemical behavior of the modified electrodes was investigated by cyclic voltammetry and electrochemical impedance spectroscopy. Under the optimal conditions, the modified electrode offered a rapid response to glucose in the range from 5 × 10⁻⁶ M to 1.1 × 10⁻³ M (R = 0.9975) with a detection limit of 3 × 10⁻⁷ M (S/N = 3) and a sensitivity of 609.8 µA · mM⁻¹. The preparation and operation of the biosensor was simple, had lower cost, and offered excellent performance due to its high sensitivity, good stability, reproducibility, and selectivity against other substances. The satisfactory results illustrated that it was promising for the determination of glucose in alkaline solutions.

Keywords:

• Cu nanoparticles/ZnO nanorod arrays
• Electrodeposition
• Glucose sensor
• Nonenzymatic

Notes

PtNFs-GO: platinum nanoflowers-graphene oxide, SWCNTs: single-walled carbon nanotubes, GCE: Glassy carbon electrode, MWCNTs: multi-walled carbon nanotubes, NiO-NFs: NiO nanofibers.

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