Spectroscopic Investigation of a Synthetic Cyanine Amine Derivative upon Various Scaffolds

Abstract

A detailed study of the supramolecular self-assembly of a cyanine amine derivative upon a variety of templates was conducted including investigation of charge properties, the rigidity of templates, and solubility. The amine derivative exhibited strong self-assembly on negatively-charged templates such as carboxymethyl amylose and carboxymethyl cellulose, and generated red-shifted absorption and enhanced fluorescence, which are characteristics of J-aggregation. Much less self-aggregation was observed for lower negatively-charged templates such as hyaluronic acid. The rigidity of templates had a great impact on self-aggregation in terms of no appreciable J- or H-aggregation observed on rigid Laponite clay. Cyanine amine existed in the molecular state with self-aggregates. For the carboxymethyl cellulose/cyanine amine system, the order of mixing each component impacted the aggregation of cyanine amine: carboxymethyl cellulose to cyanine amine mainly led to J-aggregation. In contrast, H-aggregation was dominant in cyanine amine to carboxymethyl cellulose.

Keywords:

• Carboxymethyl amylose
• Carboxymethyl cellulose
• H-aggregation
• J-aggregation
• Supramolecular self-assembly

Notes

^a CA: cyanine amine; CMA: carboxymethyl amylase; CMC: carboxymethyl cellulose; HA: hyaluronic acid; LC: Laponite clay.

^b NA: not available.