Potassium Periodate–Luminol–Silver Nanoparticles as a New Chemiluminescence System and its Application to Detect Fenoterol and Orciprenaline

Abstract

In the presence of silver nanoparticles, fenoterol and orciprenaline were shown to enhance the chemiluminescence of the potassium periodate-luminol chemiluminescence system. Therefore, a new method for the determination of fenoterol and orciprenaline was developed. The catalytic effect of silver nanoparticles upon the reaction of potassium periodate and luminol was studied. The chemiluminescence characteristics of potassium periodate, luminal, and silver nanoparticles with fenoterol and orciprenaline were studied. Using univariate design, the factors influencing chemiluminescence were optimized. The optimal experimental conditions were 60 µmol L⁻¹ of potassium periodate, 80 µmol L⁻¹ of luminol, 6 mmol L⁻¹ of sodium hydroxide, 2 µmol L⁻¹ of silver nanoparticles, and a flow rate of 2.0 mL min⁻¹. The system permitted 200 injections per hour. The linear dynamic ranges were between 0.6 and 10 ng mL⁻¹ for fenoterol and 0.4 and 10 ng mL⁻¹ for orciprenaline, with limits of detection of 0.1 ng mL⁻¹ for fenoterol and 0.1 ng mL⁻¹ for orciprenaline. The method was successfully employed to determine fenoterol and orciprenaline with recoveries in the range of 97.5% to 99.9%. Chemiluminescence reaction mechanisms for these systems were proposed.

Keywords:

• Chemiluminescence
• Flow injection
• Luminol
• Silver nanoparticles