Selective Electrochemical Determination of Salicylic Acid in Wheat Using Molecular Imprinted Polymers

ABSTRACT

Salicylic acid is a phytohormone, playing crucial roles in signal transduction, crop growth, and development, and defense to environmental challenges. In this study, a highly selective electrochemical sensor was designed and used to determine salicylic acid using molecularly imprinted polymers for recognition. The electrochemical sensor was fabricated via stepwise modification of gold nanoparticle–graphene–chitosan and molecularly imprinted polymers on a glassy carbon electrode. With electrochemical deposition, a gold nanoparticle–graphene–chitosan film was deposited on the glassy carbon electrode and enhanced the sensitivity. Molecularly imprinted polymers with adsorbed template salicylic acid were added to the surface of the modified electrode. Cyclic voltammetry and electrochemical impedance spectroscopy were used to characterize the modified electrodes. Salicylic acid in wheat was quantified by the sensor using the molecularly imprinted polymer/gold nanoparticle–graphene–chitosan/glassy carbon electrode. Concentrations of salicylic acid from 5 × 10⁻¹⁰ to 5 × 10⁻⁵ mol L⁻¹ were determined showing that the developed sensor was suitable for the analysis of food.

KEYWORDS:

• Electrochemical sensor
• glassy carbon electrode
• gold nanoparticle–graphene–chitosan
• molecularly imprinted polymers
• salicylic acid

Additional information

Funding

The authors acknowledge the financial support of the National Natural Science Foundation of China (No. 21577064).