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FLUORESCENCE

Convenient Determination of Sulfamethazine in Milk by Novel Ratiometric Fluorescence with Carbon and Quantum Dots with On-site Naked-eye Detection and Low Interferences

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Pages 2099-2113 | Received 21 Sep 2017, Accepted 05 Nov 2017, Published online: 16 Apr 2018
 

ABSTRACT

Sulfamethazine, one of the most widely applied feed additives, has been shown to cause negative health effects to humans. In the present work, a novel and facile fluorescence visual detection probe was established to determine sulfamethazine in milk samples with naked-eye detection. Considering the good stability, excellent optical properties, and easy synthesis, blue-emission carbon dots were used as the standard signal and red-emission CdTe quantum dots as the responsive signal for the determination of sulfamethazine. The fluorescence intensity of red-emission CdTe quantum dots was gradually quenched with increasing concentration of sulfamethazine, while the blue-emission carbon dots response remained constant. Apparent color variations were observed by naked-eye detection in the concentration range from 9.0 to 54 µmol · L−1. In addition, the presented strategy was shown to be promising to provide a rapid, facile, and sensitive method for the determination of sulfamethazine in milk samples with few interferences.

Acknowledgments

The authors wish to thank the National Natural Science Foundation of China (21407057, 21507045), and National Science Foundation of Jiangsu Province (BK20140534), China Postdoctoral Science Foundation Funded Project (2014M56159), and Postdoctoral Science Foundation funded Project of Jiangsu Province (1401108C).

Additional information

Funding

This work was supported by the National Natural Science Foundation of China [Grant Number 21407057, 21507045], China Postdoctoral Science Foundation Funded Project [Grant Number 2014M56159], Postdoctoral Science Foundation funded Project of Jiangsu Province [Grant Number 1401108C], and the National Science Foundation of Jiangsu Province [Grant Number BK20140534].

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