![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
Methods for the assay of glafenine and floctafenine with their respective degradation products, glafenic acid and floctafenic acid, in combination have been described. The first derivative spectrophotometric method (D1-) and the differential derivative (first, ΔD1 second ΔD2) method have been used for the assay of the intact drugs in the presence of 4‐25% of the corresponding acids. The latter could be also determined through ion pair salt formation with basic fuchsin. That method gave highly accurate results for glafenic acid and floctafenic acid recovery even in the presence of the corresponding intact drugs constituting up to 85% of the mixture.
