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Pharmaceutical Analysis

Applications of Cellulose-Based Chiral Stationary Phases in Resolution of Drug Racemates a Mini Review

Pages 231-238 | Received 25 Sep 1991, Accepted 01 Oct 1991, Published online: 23 Sep 2006
 

Abstract

An overview of various cellulose-based chiral stationary phases (CSP's) which are commercially available for direct separation of drug racemates to their corresponding enantiomers is presented. The advantages, disadvatanges, and mechanisms of resolution of these CSP's are briefly discussed. Examples of baseline resolution of some drug racemates are presented and the number of successful resolutions on these CSP's is increasing rapidly.

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